Efficacy of colistin-based combinations against pandrug-resistant whole-genome-sequenced Klebsiella pneumoniae isolated from hospitalized patients in Egypt: an in vitro/vivo comparative study

Efficacy of colistin-based combinations against pandrug-resistant whole-genome-sequenced Klebsiella pneumoniae isolated from hospitalized patients in Egypt: an in vitro/vivo comparative study

Abstract Background Colistin resistance significantly constrains available treatment options and results in the emergence of pandrug-resistant (PDR) strains. Treating PDR infections is a major public health issue. A promising solution lies in using colistin-based combinations. Despite the availabili...

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Bibliographic Details
Main Authors: Eriny T. Attalla, Amal M. Khalil, Azza S. Zakaria, Rhiannon Evans, Nesrin S. Tolba, Nelly M. Mohamed
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Gut Pathogens
Subjects:
Klebsiella pneumoniae
Pandrug-resistant
Intensive care units
Egypt
Colistin resistance
Whole-genome sequencing
Online Access:https://doi.org/10.1186/s13099-024-00667-z
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https://doi.org/10.1186/s13099-024-00667-z

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