Retention rate of TNF inhibitors versus IL-17 inhibitors in ankylosing spondylitis patients with prior biologics experience

Retention rate of TNF inhibitors versus IL-17 inhibitors in ankylosing spondylitis patients with prior biologics experience

Abstract Background For patients with ankylosing spondylitis (AS) who experience inefficacy or adverse events with biologics, no recommendations exist regarding the preference for class cycling or switching as a second- or higher-line biologics. Previous studies on the drug retention of TNF and IL-1...

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Bibliographic Details
Main Authors: Jiwon Yang, Bong-Woo Lee, Youngjae Park, Ji Hyeon Ju, Wan-Uk Kim, Sung-Hwan Park, Seung-Ki Kwok, Jennifer Jooha Lee
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Arthritis Research & Therapy
Subjects:
Ankylosing spondylitis
TNF inhibitors
IL-17 inhibitors
Biologics
Second or higher line
Drug retention
Online Access:https://doi.org/10.1186/s13075-025-03601-z
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https://doi.org/10.1186/s13075-025-03601-z

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