Identification of pharmacophore synergism for optimization of estrogen receptor beta binders for hormone dependent forms of breast cancer

Identification of pharmacophore synergism for optimization of estrogen receptor beta binders for hormone dependent forms of breast cancer

Certain forms of breast cancer, particularly influenced by estrogen hormone, prompt the investigation of estrogen receptors as potential targets for therapeutic interventions. The drug discovery pipeline against breast cancer requires the identification and retention of crucial pharmacophoric featur...

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Bibliographic Details
Main Authors: Rania A. Hussien, Fatmah Ali S. Alasmary, Vijay H. Masand, Abdul Samad, Rahul D. Jawarkar, Gaurav S. Masand, Sami A. Al-Hussain, Magdi E.A. Zaki
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Chemical Physics Impact
Subjects:
Brest cancer
Estrogen receptor beta
Pharmacophore Pattern
QSAR
Online Access:http://www.sciencedirect.com/science/article/pii/S266702242500060X
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