Genetic variants in HLA-DQA1/DQB1 genes modulate the risk of gestational diabetes mellitus in a southern Chinese population

Genetic variants in HLA-DQA1/DQB1 genes modulate the risk of gestational diabetes mellitus in a southern Chinese population

BackgroundGestational diabetes mellitus (GDM) is an endocrine disorder that occurs easily in women during pregnancy. HLA-DQA1/DQB1 genes play a crucial role in the regulation of the human immune and endocrine systems, potentially influencing the pathogenesis of GDM.ObjectiveTo explore the associatio...

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Bibliographic Details
Main Authors: Lijie Nie, Yan Sun, Ruiqi Li, Qiulian Liang, Guocun Deng, Xinyu He, Yifei Zeng, Hui Zheng, Xinhe Xiao, Xiaodong Ding, Jian Huang, Xiangyuan Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Endocrinology
Subjects:
gestational diabetes mellitus
HLA-DQA1/DQB1
risk
variant
gene-gene interaction
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2025.1511561/full
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https://www.frontiersin.org/articles/10.3389/fendo.2025.1511561/full

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