Tandem CAR-T cell therapy: recent advances and current challenges

CAR-T cell therapy has revolutionized cancer treatment. However, despite the achievements of this approach, there are still clinical challenges to address, such as antigen loss and the design of an optimal CAR structure. Multi-targeted CAR-T therapies, including tandem CAR-T cells, have emerged as a...

Full description

Saved in:
Bibliographic Details
Main Authors: Sara Gómez-Melero, Fakhri Hassouneh, Isabel M. Vallejo-Bermúdez, Eduardo Agüera-Morales, Rafael Solana, Javier Caballero-Villarraso
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1546172/full
Tags: Add Tag
No Tags, Be the first to tag this record!