Pathological complete response, histologic grade, and level of stromal tumor-infiltrating lymphocytes in ER + HER2- breast cancer

Pathological complete response, histologic grade, and level of stromal tumor-infiltrating lymphocytes in ER + HER2- breast cancer

Abstract Background Recent trials have integrated immune checkpoint inhibitors (ICIs) into neoadjuvant chemotherapy (NAC) in patients with estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative breast cancer of histologic grade (HG) III. We assessed the pathologica...

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Bibliographic Details
Main Authors: Seung Ho Baek, Min Ji Lee, Yoonwon Kook, Soong June Bae, Joon Jeong, Yoon Jin Cha, Sung Gwe Ahn
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Breast Cancer Research
Subjects:
Immune checkpoint inhibitors
Neoadjuvant chemotherapy
Estrogen receptor-positive
Human epidermal growth factor receptor 2-negative
Pathological complete response
Stromal tumor-infiltrating lymphocytes
Online Access:https://doi.org/10.1186/s13058-025-01999-7
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https://doi.org/10.1186/s13058-025-01999-7

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