Systematic network pharmacology and experimental validation reveal anti-glioma mechanisms of ganoderma lucidum via multi-target regulation

Abstract Background Glioma is the most common and lethal primary brain tumor with limited therapeutic options and poor prognosis. Traditional Chinese medicine (TCM) offers a promising avenue for discovering multi-target agents against complex diseases. Ganoderma lucidum (Lingzhi), a well-known medic...

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Bibliographic Details
Main Authors: Xue Mei, Jufen Zhang, Lu Chen, Fang Wang
Format: Article
Language:English
Published: Springer 2025-08-01
Series:Discover Oncology
Subjects:
Online Access:https://doi.org/10.1007/s12672-025-03280-x
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