Bacterial type IV secretion system induces specific and nonspecific protective immunity

Bacterial type IV secretion system induces specific and nonspecific protective immunity

ABSTRACT Pathogenic microbes trigger rapid and robust innate immune responses that effectively restrict pathogen replication and promote long-lasting adaptive immunity. The differential recognition of pathogenic versus non-pathogenic microbes occurs through the detection of host cell damage or patho...

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Main Authors: Fernanda V. S. Castanheira, Marcelo S. F. Pereira, Marco A. Ataide, Danielle P. A. Mascarenhas, Rhanoica O. Guerra, Gustavo F. S. Quirino, Fausto Almeida, Dario S. Zamboni
Format: Article
Language:English
Published: American Society for Microbiology 2025-08-01
Series:mBio
Subjects:
Legionella pneumophila
type IV secretion system
infection
immunity
innate instruction of adaptive immunity
Online Access:https://journals.asm.org/doi/10.1128/mbio.00448-25
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https://journals.asm.org/doi/10.1128/mbio.00448-25

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