Mitochondrial genomic alterations in cholangiocarcinoma cell lines.

Cholangiocarcinoma (CCA) is a diverse collection of malignant tumors that originate in the bile ducts. Mitochondria, the energy converters in eukaryotic cells, contain circular mitochondrial DNA (mtDNA) which has a greater mutation rate than nuclear DNA. Heteroplasmic variations in mtDNA may suggest...

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Main Authors: Athitaya Faipan, Sirinya Sitthirak, Arporn Wangwiwatsin, Nisana Namwat, Poramate Klanrit, Attapol Titapun, Apiwat Jareanrat, Vasin Thanasukarn, Natcha Khuntikeo, Luke Boulter, Hasaya Dokduang, Watcharin Loilome
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0323844
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