The predictive role of PD-L1 expression and CD8 + TIL levels in determining the neoadjuvant chemotherapy response in advanced ovarian cancer

The predictive role of PD-L1 expression and CD8 + TIL levels in determining the neoadjuvant chemotherapy response in advanced ovarian cancer

Abstract Objective To analyze how the PD-L1 expression and CD8 + tumor infiltrating lymphocyte (TIL) levels in biopsy samples before neoadjuvant chemotherapy (NACT) can predict chemotherapy response score and survival for advanced high-grade serous ovarian cancer (HGSC). Methods We retrospectively a...

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Bibliographic Details
Main Authors: T. Aliyeva, B. Y. Aktas, F. Gundogdu, E. Chalabiyev, Z. Arik, A. Usubutun
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Journal of Ovarian Research
Subjects:
Ovarian cancer
Neoadjuvant chemotherapy
PD-L1
TILs
CRS
Online Access:https://doi.org/10.1186/s13048-024-01533-x
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https://doi.org/10.1186/s13048-024-01533-x

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