Control of axonal growth and regeneration of sensory neurons by the p110delta PI 3-kinase.

Control of axonal growth and regeneration of sensory neurons by the p110delta PI 3-kinase.

The expression and function of the 8 distinct catalytic isoforms of PI 3-kinase (PI3K) in the nervous system are unknown. Whereas most PI3Ks have a broad tissue distribution, the tyrosine kinase-linked p110delta isoform has previously been shown to be enriched in leukocytes. Here we report that p110...

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Main Authors: Britta J Eickholt, Aminul I Ahmed, Meirion Davies, Evangelia A Papakonstanti, Wayne Pearce, Michelle L Starkey, Antonio Bilancio, Anna C Need, Andrew J H Smith, Susan M Hall, Frank P Hamers, Karl P Giese, Elizabeth J Bradbury, Bart Vanhaesebroeck
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-09-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0000869&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0000869&type=printable

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