Concurrent Pulmonary and Cerebellar Cryptococcus Gattii Cryptococcoma in an Apparently Immunocompetent Patient in Florida
Cryptococcus infection is caused by one of the two species, Cryptococcus neoformans, or the less common Cryptococcus gattii. While Cryptococcus neoformans commonly infects the immunocompromised population, Cryptococcus gattii has been seen more frequently in immunocompetent patients. Many seemingly...
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Format: | Article |
Language: | English |
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Wiley
2021-01-01
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Series: | Case Reports in Infectious Diseases |
Online Access: | http://dx.doi.org/10.1155/2021/5564520 |
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author | Benjamin Billings Neeka Akhavan Amy Vittor Ying Nagoshi |
author_facet | Benjamin Billings Neeka Akhavan Amy Vittor Ying Nagoshi |
author_sort | Benjamin Billings |
collection | DOAJ |
description | Cryptococcus infection is caused by one of the two species, Cryptococcus neoformans, or the less common Cryptococcus gattii. While Cryptococcus neoformans commonly infects the immunocompromised population, Cryptococcus gattii has been seen more frequently in immunocompetent patients. Many seemingly immunocompetent patients, however, may have unidentified underlying immunodeficiencies. Recently, antigranulocyte-macrophage colony-stimulating (GM-CSF) antibodies have been identified as a risk factor for cryptococcosis. We describe a case of disseminated Cryptococcus gattii infection in a seemingly immunocompetent young man, who is found to have anti-GM-CSF antibodies. |
format | Article |
id | doaj-art-cae1c713ba6442a88baac2cb88dbb5db |
institution | Kabale University |
issn | 2090-6625 2090-6633 |
language | English |
publishDate | 2021-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Infectious Diseases |
spelling | doaj-art-cae1c713ba6442a88baac2cb88dbb5db2025-02-03T05:44:12ZengWileyCase Reports in Infectious Diseases2090-66252090-66332021-01-01202110.1155/2021/55645205564520Concurrent Pulmonary and Cerebellar Cryptococcus Gattii Cryptococcoma in an Apparently Immunocompetent Patient in FloridaBenjamin Billings0Neeka Akhavan1Amy Vittor2Ying Nagoshi3University of Florida College of Medicine, Gainesville, FL, USADivision of General Internal Medicine, University of Florida College of Medicine, Gainesville, FL, USADivision of Infectious Disease and Global Medicine, University of Florida College of Medicine, Gainesville, FL, USADivision of General Internal Medicine, University of Florida College of Medicine, Gainesville, FL, USACryptococcus infection is caused by one of the two species, Cryptococcus neoformans, or the less common Cryptococcus gattii. While Cryptococcus neoformans commonly infects the immunocompromised population, Cryptococcus gattii has been seen more frequently in immunocompetent patients. Many seemingly immunocompetent patients, however, may have unidentified underlying immunodeficiencies. Recently, antigranulocyte-macrophage colony-stimulating (GM-CSF) antibodies have been identified as a risk factor for cryptococcosis. We describe a case of disseminated Cryptococcus gattii infection in a seemingly immunocompetent young man, who is found to have anti-GM-CSF antibodies.http://dx.doi.org/10.1155/2021/5564520 |
spellingShingle | Benjamin Billings Neeka Akhavan Amy Vittor Ying Nagoshi Concurrent Pulmonary and Cerebellar Cryptococcus Gattii Cryptococcoma in an Apparently Immunocompetent Patient in Florida Case Reports in Infectious Diseases |
title | Concurrent Pulmonary and Cerebellar Cryptococcus Gattii Cryptococcoma in an Apparently Immunocompetent Patient in Florida |
title_full | Concurrent Pulmonary and Cerebellar Cryptococcus Gattii Cryptococcoma in an Apparently Immunocompetent Patient in Florida |
title_fullStr | Concurrent Pulmonary and Cerebellar Cryptococcus Gattii Cryptococcoma in an Apparently Immunocompetent Patient in Florida |
title_full_unstemmed | Concurrent Pulmonary and Cerebellar Cryptococcus Gattii Cryptococcoma in an Apparently Immunocompetent Patient in Florida |
title_short | Concurrent Pulmonary and Cerebellar Cryptococcus Gattii Cryptococcoma in an Apparently Immunocompetent Patient in Florida |
title_sort | concurrent pulmonary and cerebellar cryptococcus gattii cryptococcoma in an apparently immunocompetent patient in florida |
url | http://dx.doi.org/10.1155/2021/5564520 |
work_keys_str_mv | AT benjaminbillings concurrentpulmonaryandcerebellarcryptococcusgattiicryptococcomainanapparentlyimmunocompetentpatientinflorida AT neekaakhavan concurrentpulmonaryandcerebellarcryptococcusgattiicryptococcomainanapparentlyimmunocompetentpatientinflorida AT amyvittor concurrentpulmonaryandcerebellarcryptococcusgattiicryptococcomainanapparentlyimmunocompetentpatientinflorida AT yingnagoshi concurrentpulmonaryandcerebellarcryptococcusgattiicryptococcomainanapparentlyimmunocompetentpatientinflorida |