Concurrent Pulmonary and Cerebellar Cryptococcus Gattii Cryptococcoma in an Apparently Immunocompetent Patient in Florida

Cryptococcus infection is caused by one of the two species, Cryptococcus neoformans, or the less common Cryptococcus gattii. While Cryptococcus neoformans commonly infects the immunocompromised population, Cryptococcus gattii has been seen more frequently in immunocompetent patients. Many seemingly...

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Main Authors: Benjamin Billings, Neeka Akhavan, Amy Vittor, Ying Nagoshi
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Infectious Diseases
Online Access:http://dx.doi.org/10.1155/2021/5564520
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author Benjamin Billings
Neeka Akhavan
Amy Vittor
Ying Nagoshi
author_facet Benjamin Billings
Neeka Akhavan
Amy Vittor
Ying Nagoshi
author_sort Benjamin Billings
collection DOAJ
description Cryptococcus infection is caused by one of the two species, Cryptococcus neoformans, or the less common Cryptococcus gattii. While Cryptococcus neoformans commonly infects the immunocompromised population, Cryptococcus gattii has been seen more frequently in immunocompetent patients. Many seemingly immunocompetent patients, however, may have unidentified underlying immunodeficiencies. Recently, antigranulocyte-macrophage colony-stimulating (GM-CSF) antibodies have been identified as a risk factor for cryptococcosis. We describe a case of disseminated Cryptococcus gattii infection in a seemingly immunocompetent young man, who is found to have anti-GM-CSF antibodies.
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institution Kabale University
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publishDate 2021-01-01
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series Case Reports in Infectious Diseases
spelling doaj-art-cae1c713ba6442a88baac2cb88dbb5db2025-02-03T05:44:12ZengWileyCase Reports in Infectious Diseases2090-66252090-66332021-01-01202110.1155/2021/55645205564520Concurrent Pulmonary and Cerebellar Cryptococcus Gattii Cryptococcoma in an Apparently Immunocompetent Patient in FloridaBenjamin Billings0Neeka Akhavan1Amy Vittor2Ying Nagoshi3University of Florida College of Medicine, Gainesville, FL, USADivision of General Internal Medicine, University of Florida College of Medicine, Gainesville, FL, USADivision of Infectious Disease and Global Medicine, University of Florida College of Medicine, Gainesville, FL, USADivision of General Internal Medicine, University of Florida College of Medicine, Gainesville, FL, USACryptococcus infection is caused by one of the two species, Cryptococcus neoformans, or the less common Cryptococcus gattii. While Cryptococcus neoformans commonly infects the immunocompromised population, Cryptococcus gattii has been seen more frequently in immunocompetent patients. Many seemingly immunocompetent patients, however, may have unidentified underlying immunodeficiencies. Recently, antigranulocyte-macrophage colony-stimulating (GM-CSF) antibodies have been identified as a risk factor for cryptococcosis. We describe a case of disseminated Cryptococcus gattii infection in a seemingly immunocompetent young man, who is found to have anti-GM-CSF antibodies.http://dx.doi.org/10.1155/2021/5564520
spellingShingle Benjamin Billings
Neeka Akhavan
Amy Vittor
Ying Nagoshi
Concurrent Pulmonary and Cerebellar Cryptococcus Gattii Cryptococcoma in an Apparently Immunocompetent Patient in Florida
Case Reports in Infectious Diseases
title Concurrent Pulmonary and Cerebellar Cryptococcus Gattii Cryptococcoma in an Apparently Immunocompetent Patient in Florida
title_full Concurrent Pulmonary and Cerebellar Cryptococcus Gattii Cryptococcoma in an Apparently Immunocompetent Patient in Florida
title_fullStr Concurrent Pulmonary and Cerebellar Cryptococcus Gattii Cryptococcoma in an Apparently Immunocompetent Patient in Florida
title_full_unstemmed Concurrent Pulmonary and Cerebellar Cryptococcus Gattii Cryptococcoma in an Apparently Immunocompetent Patient in Florida
title_short Concurrent Pulmonary and Cerebellar Cryptococcus Gattii Cryptococcoma in an Apparently Immunocompetent Patient in Florida
title_sort concurrent pulmonary and cerebellar cryptococcus gattii cryptococcoma in an apparently immunocompetent patient in florida
url http://dx.doi.org/10.1155/2021/5564520
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