Excessive MYC Orchestrates Macrophages induced Chromatin Remodeling to Sustain Micropapillary‐Patterned Malignancy in Lung Adenocarcinoma

Excessive MYC Orchestrates Macrophages induced Chromatin Remodeling to Sustain Micropapillary‐Patterned Malignancy in Lung Adenocarcinoma

Abstract Current understanding of micropapillary (MP)‐subtype lung adenocarcinoma (LUAD) remains confined to biological activities and genomic landscapes. Unraveling the major regulatory programs underlying MP patterned malignancy offers opportunities to identify more feasible therapeutic targets fo...

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Bibliographic Details
Main Authors: Xuming Song, Zehao Pan, Yi Zhang, Wenmin Yang, Te Zhang, Hui Wang, Yuzhong Chen, Xinnian Yu, Hanlin Ding, Rutao Li, Pengfei Ge, Lin Xu, Gaochao Dong, Feng Jiang
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Advanced Science
Subjects:
chromatin accessibility
M2‐like macrophages
micropapillary lung adenocarcinoma
MYC
Online Access:https://doi.org/10.1002/advs.202403851
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https://doi.org/10.1002/advs.202403851

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