Unveiling the evolution of antimicrobial peptides in gut microbes via foundation-model-powered framework

Summary: Antimicrobial resistance poses a major threat to public health, prompting the development of alternative therapies such as antimicrobial peptides (AMPs). Protein language models (PLMs) have advanced protein structure and function predictions, facilitating AMP discovery. We developed antimic...

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Main Authors: Wenhui Li, Baicheng Huang, Menghao Guo, Zihan Zeng, Tao Cai, Linqing Feng, Xinpeng Zhang, Ling Guo, Xianyue Jiang, Yanbin Yin, Ercheng Wang, Xingxu Huang, Jinfang Zheng
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Cell Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725005443
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