Plasma microRNA signatures of aging and their links to health outcomes and mortality: findings from a population-based cohort study

Plasma microRNA signatures of aging and their links to health outcomes and mortality: findings from a population-based cohort study

Abstract Background MicroRNAs are small non-coding RNAs that regulate gene expression post-transcriptionally and show differential expression in various tissues with aging phenotypes. Detectable in circulation, extracellular microRNAs reflect (patho)physiological processes and hold promise as biomar...

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Main Authors: Lieke M. Kuiper, Michelle M. J. Mens, Julia W. Wu, Jaap Goudsmit, Yuan Ma, Liming Liang, Albert Hofman, Trudy Voortman, M. Arfan Ikram, Jeroen G. J. van Rooij, Joyce B. J. van Meurs, Mohsen Ghanbari
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Genome Medicine
Subjects:
MicroRNA
Aging
Biomarker
Biological age
Mortality
Frailty
Online Access:https://doi.org/10.1186/s13073-025-01437-5
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https://doi.org/10.1186/s13073-025-01437-5

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