ATP Alters the Oxylipin Profiles in Astrocytes: Modulation by High Glucose and Metformin

ATP Alters the Oxylipin Profiles in Astrocytes: Modulation by High Glucose and Metformin

<b>Background:</b> Astrocytes play a key role in the inflammatory process accompanying various neurological diseases. Extracellular ATP accompanies inflammatory processes in the brain, but its effect on lipid mediators (oxylipins) in astrocytes remains elusive. Metformin is a hypoglycemi...

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Bibliographic Details
Main Authors: Alexey I. Drozhdev, Vladislav O. Gorbatenko, Sergey V. Goriainov, Dmitry V. Chistyakov, Marina G. Sergeeva
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Brain Sciences
Subjects:
ATP
astrocytes
oxylipins
hyperglycemia
inflammation
metformin
Online Access:https://www.mdpi.com/2076-3425/15/3/293
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