From bench to bedside: cutting-edge applications of base editing and prime editing in precision medicine

Abstract CRISPR-based gene editing technology theoretically allows for precise manipulation of any genetic target within living cells, achieving the desired sequence modifications. This revolutionary advancement has fundamentally transformed the field of biomedicine, offering immense clinical potent...

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Bibliographic Details
Main Authors: Weihui Xu, Shiyao Zhang, Huan Qin, Kai Yao
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-024-05957-3
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