Differences in phenotype between long-lived memory B cells against Plasmodium falciparum merozoite antigens and variant surface antigens.

Differences in phenotype between long-lived memory B cells against Plasmodium falciparum merozoite antigens and variant surface antigens.

Plasmodium falciparum infections elicit strong humoral immune responses to two main groups of antigens expressed by blood-stage parasites: merozoite antigens that are involved in the erythrocyte invasion process and variant surface antigens that mediate endothelial sequestration of infected erythroc...

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Main Authors: Raphael A Reyes, Louise Turner, Isaac Ssewanyana, Prasanna Jagannathan, Margaret E Feeney, Thomas Lavstsen, Bryan Greenhouse, Sebastiaan Bol, Evelien M Bunnik
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-10-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1012661
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https://doi.org/10.1371/journal.ppat.1012661

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