Spatially and temporally mismatched blood flow and neuronal activity by high-intensity intracortical microstimulation

Spatially and temporally mismatched blood flow and neuronal activity by high-intensity intracortical microstimulation

Introduction: Intracortial microstimulation (ICMS) is widely used in neuroprosthetic brain-machine interfacing, particularly in restoring lost sensory and motor functions. Spiking neuronal activity requires increased cerebral blood flow to meet local metabolic demands, a process conventionally denot...

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Bibliographic Details
Main Authors: Alexandra Katherine Isis Yonza, Lechan Tao, Xiao Zhang, Dmitry Postnov, Krzysztof Kucharz, Barbara Lind, Antonios Asiminas, Anpan Han, Victor Sonego, Kayeon Kim, Changsi Cai
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Brain Stimulation
Subjects:
Intracortical microstimulation (ICMS)
Neurovascular coupling (NVC)
Two-photon imaging (TPM)
Laser speckle imaging (LSI)
Vascular mural cells (VMC)
Cerebral blood flow
Online Access:http://www.sciencedirect.com/science/article/pii/S1935861X25000968
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