Network pharmacological approach combined with weighted gene co-expression network analysis identifies CDKN2A as the keg target of Changweiqing against colorectal cancer

Network pharmacological approach combined with weighted gene co-expression network analysis identifies CDKN2A as the keg target of Changweiqing against colorectal cancer

Abstract Background and objective Changweiqing (CWQ) is a Chinese herbal formula for the treatment of the gastrointestinal tract diseases, but its role in the treatment of colorectal cancer (CRC) has not been clarified. This study aimed to explore the molecular mechanism of CWQ in CRC treatment thro...

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Bibliographic Details
Main Authors: Ma Zushuai, Ji Yanrong, Zhao Chengdu, Zhu Xu, Ding Qianshan
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Hereditas
Subjects:
Changweiqing
Colorectal cancer
CDKN2A
Network pharmacology
WGCNA
Online Access:https://doi.org/10.1186/s41065-025-00405-8
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https://doi.org/10.1186/s41065-025-00405-8

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