Senecio scandens Buch.-Ham. polysaccharides exert anti-atopic dermatitis effects by modulating gut microbiota and the MAPK/NF-κB pathway

Senecio scandens Buch.-Ham. polysaccharides exert anti-atopic dermatitis effects by modulating gut microbiota and the MAPK/NF-κB pathway

This study aims to extract polysaccharides from Senecio scandens Buch.-Ham. (SSP) using alcohol and water extraction and investigate whether they can be delivered orally to treat atopic dermatitis (AD). In vivo investigations demonstrated that SSP notably improved inflammation in mice, reducing ear...

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Bibliographic Details
Main Authors: Zhi-Qin Hu, Shu-Shu Xie, Ming-Yuan Zhou, Yu-Chi Chen, Fang-Mei Zhou, Zhi-Shan Ding, Xiao-Qing Ye
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Pharmacology
Subjects:
Senecio scandens Buch.-Ham.
polysaccharides
atopic dermatitis
anti-inflammatory
gut–skin axis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1573135/full
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https://www.frontiersin.org/articles/10.3389/fphar.2025.1573135/full

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