SPAG6 Promotes Multiple Myeloma Through Activation of the MAPK/ERK Signaling Pathway

SPAG6 Promotes Multiple Myeloma Through Activation of the MAPK/ERK Signaling Pathway

BackgroundSperm - associated antigen 6 (SPAG6), a member of the cancer/testis antigen (CTA) family, has been linked to multiple hematologic malignancies. Nevertheless, its role in multiple myeloma (MM) remains unclear.MethodsBioinformatics, tissue specimens from plasma cell tumors, and bone marrow s...

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Bibliographic Details
Main Authors: Junnan Li, Xinyu Yan, Li Ding, Jiaxiu Yin, Ping Li, Lin Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Pharmacology
Subjects:
SPAG6, sperm-associated antigen 6
DUSP1, dual specificity phosphatase
MAPK, mitogen-activated protein kinase
expresion
multiple myeloma
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1572621/full
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https://www.frontiersin.org/articles/10.3389/fphar.2025.1572621/full

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