Human bone marrow mesenchimal stem cells growth rate dynamics, immunophenotype and genetic stability on early and late passages at <i>ex vivo</i> culturing

Human bone marrow mesenchimal stem cells growth rate dynamics, immunophenotype and genetic stability on early and late passages at <i>ex vivo</i> culturing

Human mesenchimal stem cells (MSC) growth dynamics, immunophenotype change, genetic stability on early (3—4) and late (10—12) passages at in vitro culturing was studied. Results of bone marrow stromal fibroblasts culturing (n=25) from allogeneic transplant recipients with hematological disorders are...

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Main Authors: E. Yu. Osipova, V. A. Nikitina, T. A. Astrelina, A. Yu. Ustyugov, E. V. Dmitrieva, B. B. Purbueva, E. V. Skorobogatova, T. V. Schamanckaya, Z. M. Dischlevaya, M. V. Yakovleva, O. A. Maiorova, L. D. Katosova, S. A. Roumiantsev, N. P. Bochkov
Format: Article
Language:Russian
Published: ABV-press 2022-11-01
Series:Онкогематология
Subjects:
mesenchimal stem cells
passage
immunophenotype
proliferating activity
genetic stability
expansion <i>ex vivo</i>
Online Access:https://oncohematology.abvpress.ru/ongm/article/view/710
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