HBV activates hepatic stellate cells through RUNX2/ITGBL1 axis

Abstract Background Chronic hepatitis B (CHB) remains a global health challenge, with liver fibrosis serving as a critical determinant of disease progression. Despite antiviral treatments, liver fibrosis often persists in CHB patients, highlighting the need for additional biomarkers and therapeutic...

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Bibliographic Details
Main Authors: Fengchun Shi, Wei Tan, Wei Huang, Fei Ye, Mingjie Wang, Yongxiang Wang, Xinxin Zhang, Demin Yu
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Virology Journal
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Online Access:https://doi.org/10.1186/s12985-025-02749-z
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