Preeclampsia is associated with alterations in the p53-pathway in villous trophoblast.

Preeclampsia is associated with alterations in the p53-pathway in villous trophoblast.

<h4>Background</h4>Preeclampsia (PE) is characterized by exaggerated apoptosis of the villous trophoblast of placental villi. Since p53 is a critical regulator of apoptosis we hypothesized that excessive apoptosis in PE is mediated by abnormal expression of proteins participating in the...

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Main Authors: Andrew N Sharp, Alexander E P Heazell, Dora Baczyk, Caroline E Dunk, Helen A Lacey, Carolyn J P Jones, Jonathan E Perkins, John C P Kingdom, Philip N Baker, Ian P Crocker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0087621&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0087621&type=printable

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