Role of interleukin-15 and interleukin-18 in the secretion of sIL-6R and sgp130 by human neutrophils

Background: Available data indicate that neutrophils (PMN) produce a wide range of cytokines with the potential to modulate immune response. Recent investigation have shown that interleukin (IL)-15 and IL-18 potentiated several functions of normal neutrophils. It has been reported that IL-18-induced...

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Main Authors: E. Jablonska, M. Marcinczyk
Format: Article
Language:English
Published: Wiley 2003-01-01
Series:Mediators of Inflammation
Subjects:
Online Access:http://dx.doi.org/10.1080/0962935031000134905
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author E. Jablonska
M. Marcinczyk
author_facet E. Jablonska
M. Marcinczyk
author_sort E. Jablonska
collection DOAJ
description Background: Available data indicate that neutrophils (PMN) produce a wide range of cytokines with the potential to modulate immune response. Recent investigation have shown that interleukin (IL)-15 and IL-18 potentiated several functions of normal neutrophils. It has been reported that IL-18-induced cytokine production may be significantly enhanced by coincident addition of IL-15.
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series Mediators of Inflammation
spelling doaj-art-ca2d02c8ab6843c49c19f7380b91b3da2025-02-03T05:58:46ZengWileyMediators of Inflammation0962-93511466-18612003-01-0112317918310.1080/0962935031000134905Role of interleukin-15 and interleukin-18 in the secretion of sIL-6R and sgp130 by human neutrophilsE. Jablonska0M. Marcinczyk1Department of Immunology, Medical University of Bialystok, Waszyngtona 15A, Bialystok 15-274, PolandDepartment of Immunology, Medical University of Bialystok, Waszyngtona 15A, Bialystok 15-274, PolandBackground: Available data indicate that neutrophils (PMN) produce a wide range of cytokines with the potential to modulate immune response. Recent investigation have shown that interleukin (IL)-15 and IL-18 potentiated several functions of normal neutrophils. It has been reported that IL-18-induced cytokine production may be significantly enhanced by coincident addition of IL-15.http://dx.doi.org/10.1080/0962935031000134905NeutrophilsSoluble interleukin-6 receptor αSoluble gp130Interleukin-15Interleukin-18.
spellingShingle E. Jablonska
M. Marcinczyk
Role of interleukin-15 and interleukin-18 in the secretion of sIL-6R and sgp130 by human neutrophils
Mediators of Inflammation
Neutrophils
Soluble interleukin-6 receptor α
Soluble gp130
Interleukin-15
Interleukin-18.
title Role of interleukin-15 and interleukin-18 in the secretion of sIL-6R and sgp130 by human neutrophils
title_full Role of interleukin-15 and interleukin-18 in the secretion of sIL-6R and sgp130 by human neutrophils
title_fullStr Role of interleukin-15 and interleukin-18 in the secretion of sIL-6R and sgp130 by human neutrophils
title_full_unstemmed Role of interleukin-15 and interleukin-18 in the secretion of sIL-6R and sgp130 by human neutrophils
title_short Role of interleukin-15 and interleukin-18 in the secretion of sIL-6R and sgp130 by human neutrophils
title_sort role of interleukin 15 and interleukin 18 in the secretion of sil 6r and sgp130 by human neutrophils
topic Neutrophils
Soluble interleukin-6 receptor α
Soluble gp130
Interleukin-15
Interleukin-18.
url http://dx.doi.org/10.1080/0962935031000134905
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AT mmarcinczyk roleofinterleukin15andinterleukin18inthesecretionofsil6randsgp130byhumanneutrophils