High-resolution mass spectrometry measurement of N-terminal carbamylated hemoglobin as a potential marker for chronic diseases with elevated blood urea levels

High-resolution mass spectrometry measurement of N-terminal carbamylated hemoglobin as a potential marker for chronic diseases with elevated blood urea levels

Introduction: N-terminal carbamylated hemoglobin (CarHb) reflects long-term blood urea levels and has potential as a marker for chronic kidney disease (CKD) and other chronic conditions with elevated blood urea levels. A liquid chromatography-high-resolution mass spectrometry (LC-HR-MS) method was d...

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Bibliographic Details
Main Authors: Fangjun Chen, Priscilla S.-W. Yeung, Carolyn V. Wong, Ruben Y. Luo
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Journal of Mass Spectrometry and Advances in the Clinical Lab
Subjects:
High-resolution mass spectrometry
Carbamylated hemoglobin
Chronic disease
Blood urea
Online Access:http://www.sciencedirect.com/science/article/pii/S2667145X2500001X
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