Electronic health records-based research in Cardiology: The time has come for pragmatic trials

Randomized clinical trials (RCTs) are the cornerstone of evidence-based medicine, as they minimize bias in the allocation of interventions. However, RCTs performed in a very selective population and overcontrolled conditions may impair the generalizability of results. Moreover, increasing running co...

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Bibliographic Details
Main Authors: Daniel Seabra, Afonso Oliveira, Cristina Gavina
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Revista Portuguesa de Cardiologia
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Online Access:http://www.sciencedirect.com/science/article/pii/S0870255125001544
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