Lipid Nanoparticles Formulated with a Novel Cholesterol-Tailed Ionizable Lipid Markedly Increase mRNA Delivery Both in vitro and in vivo

Lipid Nanoparticles Formulated with a Novel Cholesterol-Tailed Ionizable Lipid Markedly Increase mRNA Delivery Both in vitro and in vivo

Ju Hyeong Jeon,1 Huabin Zhu,1 Jane Qin,1 Luyao Wang,2 Stephanie Mou,1 Laura Katherine Langston,1 Ramesh Marasini,1 Jianzhu Chen,3 Renhuan Xu,1 Shuna Li,2 Xinle Cui1 1ARV Technologies, Inc, North Bethesda, MD, 20852, USA; 2Department of Otorhinolaryngology-Head and Neck Surgery, Xinhua Hospital, Shan...

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Main Authors: Jeon JH, Zhu H, Qin J, Wang L, Mou S, Langston LK, Marasini R, Chen J, Xu R, Li S, Cui X
Format: Article
Language:English
Published: Dove Medical Press 2025-07-01
Series:International Journal of Nanomedicine
Subjects:
Novel Ionizable lipids
ribonucleic acid
protein expression
vaccine
neutralizing antibodies
Online Access:https://www.dovepress.com/lipid-nanoparticles-formulated-with-a-novel-cholesterol-tailed-ionizab-peer-reviewed-fulltext-article-IJN
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https://www.dovepress.com/lipid-nanoparticles-formulated-with-a-novel-cholesterol-tailed-ionizab-peer-reviewed-fulltext-article-IJN

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