Immunohistochemical expression of markers Ki-67, neun, synaptophysin, p53 and HER2 in medulloblastoma and its correlation with clinicopathological parameters Expressão imunoistoquímica dos marcadores Ki-67, neun, sinaptofisina, p53 e HER2 em meduloblastoma e sua correlação com os parâmetros clínico-patológicos

Immunohistochemical expression of markers Ki-67, neun, synaptophysin, p53 and HER2 in medulloblastoma and its correlation with clinicopathological parameters Expressão imunoistoquímica dos marcadores Ki-67, neun, sinaptofisina, p53 e HER2 em meduloblastoma e sua correlação com os parâmetros clínico-patológicos

Medulloblastoma (MB) is the most common malignant brain tumor in childhood. The alterations found include: presence of oncoproteins p53 and HER2, elevated mitotic index, and presence of neuronal differentiation. The aim of this study was to determine the immunohistochemical expression of markers Ki-...

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Bibliographic Details
Main Authors: Rosalva Thereza Meurer, Daniele Tondolo Martins, Arlete Hilbig, Marlise de Castro Ribeiro, Adriana Vial Roehe, Ligia Maria Barbosa-Coutinho, Marilda da Cruz Fernandes
Format: Article
Language:English
Published: Thieme Revinter Publicações 2008-06-01
Series:Arquivos de Neuro-Psiquiatria
Subjects:
meduloblastoma
imunoistoquímica
Ki-67
NeuN
sinaptofisina
HER2
p53
sobrevida
medulloblastoma
immunohistochemistry
synaptophysin
survival analysis
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2008000300020
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