Contract to kill: GNAS mutation

Abstract The mutation in Gsα-coding GNAS exons, popular as gsp oncogene, is the most frequent mutation across all heterotrimeric G proteins involved in oncogenesis. GNAS R201, the most frequently mutated, followed by Q227, are found predominantly across various neoplasms and cancers such as IPMN, pi...

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Bibliographic Details
Main Authors: Pratima Raut, Poompozhil Mathivanan, Surinder K. Batra, Moorthy P. Ponnusamy
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Molecular Cancer
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Online Access:https://doi.org/10.1186/s12943-025-02247-4
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