The EPA oxylipin, 12-HEPE, directly regulates human platelet activity

Arterial thrombosis, driven by platelet hyperactivity, is the underlying pathophysiology of most major cardiovascular events. Dietary fish oil supplementation containing ω-3 polyunsaturated fatty acids (PUFAs) elicits cardiovascular protection in at-risk patients. Studies have attributed the cardiov...

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Bibliographic Details
Main Authors: Krista Goerger, Livia Stanger, Andrew Rickenberg, Anthony Nguyễn, Taekyu Lee, Theodore R. Holman, Michael Holinstat
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Journal of Lipid Research
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Online Access:http://www.sciencedirect.com/science/article/pii/S0022227525000677
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