Promoting effects of NaCl and KCl stresses on astaxanthin yield in Microcystis flos-aquae

This study was to uncover the astaxanthin accumulation mechanism of Microcystis flos-aquae stressed by NaCl and KCl and select the optimal condition for astaxanthin production. Both of NaCl and KCl stresses showed inhibiting effects on M. flos-aquae growth by reducing photosynthetic abilities and ca...

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Main Authors: Junjie Ma, Zhehan Yang, Zhuxin Jin, Lexin Huang, Yinggang Wei, Wangbo Chen, Zhaojiang Zuo
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Food Chemistry: X
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Online Access:http://www.sciencedirect.com/science/article/pii/S2590157525002895
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author Junjie Ma
Zhehan Yang
Zhuxin Jin
Lexin Huang
Yinggang Wei
Wangbo Chen
Zhaojiang Zuo
author_facet Junjie Ma
Zhehan Yang
Zhuxin Jin
Lexin Huang
Yinggang Wei
Wangbo Chen
Zhaojiang Zuo
author_sort Junjie Ma
collection DOAJ
description This study was to uncover the astaxanthin accumulation mechanism of Microcystis flos-aquae stressed by NaCl and KCl and select the optimal condition for astaxanthin production. Both of NaCl and KCl stresses showed inhibiting effects on M. flos-aquae growth by reducing photosynthetic abilities and causing reactive oxygen species accumulation. With raising the two salt concentrations, astaxanthin content and yield gradually increased, and the highest accumulation was under 300 mM for each salt, which should result from the up-regulation of 6 related genes promoting the precursor (β-carotene and zeaxanthin) transformation. KCl stress was more effective for improving astaxanthin yield than NaCl stress, which was strongly related with the salt concentration and astaxanthin content. Compared with other potential suitable conditions (35°C and purple light), 300 mM KCl also exhibited maximum effect on astaxanthin accumulation. Therefore, M. flos-aquae is first identified to synthesize astaxanthin, and KCl stress is more favorable to the compound production.
format Article
id doaj-art-c98ba12ffab545d89fd9ad1e19cde614
institution Kabale University
issn 2590-1575
language English
publishDate 2025-04-01
publisher Elsevier
record_format Article
series Food Chemistry: X
spelling doaj-art-c98ba12ffab545d89fd9ad1e19cde6142025-08-20T03:49:45ZengElsevierFood Chemistry: X2590-15752025-04-012710244210.1016/j.fochx.2025.102442Promoting effects of NaCl and KCl stresses on astaxanthin yield in Microcystis flos-aquaeJunjie Ma0Zhehan Yang1Zhuxin Jin2Lexin Huang3Yinggang Wei4Wangbo Chen5Zhaojiang Zuo6National Key Laboratory for Development and Utilization of Forest Food Resources, Zhejiang A&F University, Hangzhou 311300, China; College of Forestry and Biotechnology, Zhejiang A&F University, Hangzhou 311300, ChinaNational Key Laboratory for Development and Utilization of Forest Food Resources, Zhejiang A&F University, Hangzhou 311300, China; College of Forestry and Biotechnology, Zhejiang A&F University, Hangzhou 311300, ChinaNational Key Laboratory for Development and Utilization of Forest Food Resources, Zhejiang A&F University, Hangzhou 311300, China; College of Forestry and Biotechnology, Zhejiang A&F University, Hangzhou 311300, ChinaNational Key Laboratory for Development and Utilization of Forest Food Resources, Zhejiang A&F University, Hangzhou 311300, China; College of Forestry and Biotechnology, Zhejiang A&F University, Hangzhou 311300, ChinaNational Key Laboratory for Development and Utilization of Forest Food Resources, Zhejiang A&F University, Hangzhou 311300, China; College of Forestry and Biotechnology, Zhejiang A&F University, Hangzhou 311300, ChinaNational Key Laboratory for Development and Utilization of Forest Food Resources, Zhejiang A&F University, Hangzhou 311300, China; College of Forestry and Biotechnology, Zhejiang A&F University, Hangzhou 311300, ChinaNational Key Laboratory for Development and Utilization of Forest Food Resources, Zhejiang A&F University, Hangzhou 311300, China; College of Forestry and Biotechnology, Zhejiang A&F University, Hangzhou 311300, China; Corresponding author at: National Key Laboratory for Development and Utilization of Forest Food Resources, Zhejiang A&F University, Hangzhou 311300, China.This study was to uncover the astaxanthin accumulation mechanism of Microcystis flos-aquae stressed by NaCl and KCl and select the optimal condition for astaxanthin production. Both of NaCl and KCl stresses showed inhibiting effects on M. flos-aquae growth by reducing photosynthetic abilities and causing reactive oxygen species accumulation. With raising the two salt concentrations, astaxanthin content and yield gradually increased, and the highest accumulation was under 300 mM for each salt, which should result from the up-regulation of 6 related genes promoting the precursor (β-carotene and zeaxanthin) transformation. KCl stress was more effective for improving astaxanthin yield than NaCl stress, which was strongly related with the salt concentration and astaxanthin content. Compared with other potential suitable conditions (35°C and purple light), 300 mM KCl also exhibited maximum effect on astaxanthin accumulation. Therefore, M. flos-aquae is first identified to synthesize astaxanthin, and KCl stress is more favorable to the compound production.http://www.sciencedirect.com/science/article/pii/S2590157525002895AstaxanthinGene expressionMicrocystis flos-aquaeOptimal conditionSalt stress
spellingShingle Junjie Ma
Zhehan Yang
Zhuxin Jin
Lexin Huang
Yinggang Wei
Wangbo Chen
Zhaojiang Zuo
Promoting effects of NaCl and KCl stresses on astaxanthin yield in Microcystis flos-aquae
Food Chemistry: X
Astaxanthin
Gene expression
Microcystis flos-aquae
Optimal condition
Salt stress
title Promoting effects of NaCl and KCl stresses on astaxanthin yield in Microcystis flos-aquae
title_full Promoting effects of NaCl and KCl stresses on astaxanthin yield in Microcystis flos-aquae
title_fullStr Promoting effects of NaCl and KCl stresses on astaxanthin yield in Microcystis flos-aquae
title_full_unstemmed Promoting effects of NaCl and KCl stresses on astaxanthin yield in Microcystis flos-aquae
title_short Promoting effects of NaCl and KCl stresses on astaxanthin yield in Microcystis flos-aquae
title_sort promoting effects of nacl and kcl stresses on astaxanthin yield in microcystis flos aquae
topic Astaxanthin
Gene expression
Microcystis flos-aquae
Optimal condition
Salt stress
url http://www.sciencedirect.com/science/article/pii/S2590157525002895
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