Surgical management for periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA) syndrome: a systematic review and meta-analysis

Surgical management for periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA) syndrome: a systematic review and meta-analysis

Objective: This systematic review and meta-analysis aimed to evaluate the efficacy of surgical management, specifically total and partial tonsillectomy, for Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis (PFAPA) syndrome, focusing on symptom resolution and recurrence reducti...

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Main Authors: Luís Fernando Ferreira Cavalcante, Giovanna Costa, Sophia Massafelli Battistuta, Pedro Faria Makabe, Isadora Silva Fanucci Bueno, Bruno Yuamoto, Felipe Endrigo Gonçalves Vilela, Marco Aurélio Palazzi Sáfadi
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Jornal de Pediatria
Subjects:
Syndrome of periodic fever
Aphthous stomatitis, pharyngitis, and cervical adenitis
Tonsillectomy
Tonsillotomy
Randomized controlled trial
Meta-analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S0021755725000701
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