Double-blind, non-inferiority, randomized controlled trial of dexamethasone 4, 5 and 6 mg for preventing adverse neonatal and maternal outcomes in very preterm to late preterm pregnancies between 29 0 and 36 6 weeks of gestation: study protocol

Double-blind, non-inferiority, randomized controlled trial of dexamethasone 4, 5 and 6 mg for preventing adverse neonatal and maternal outcomes in very preterm to late preterm pregnancies between 29 0 and 36 6 weeks of gestation: study protocol

Abstract Background Premature birth poses significant health challenges, including respiratory distress syndrome (RDS). Corticosteroids reduce the incidence of RDS, but higher dexamethasone doses may lead to adverse neonatal outcomes, such as growth restriction and neurodevelopmental issues. Determi...

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Bibliographic Details
Main Authors: Saifon Chawanpaiboon, Punnanee Wutthigate, Sanitra Anuwutnavin, Sureelak Sutchritpongsa
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Reproductive Health
Subjects:
4-mg dose
5-mg dose
6-mg dose
Antenatal corticosteroids
Apnoea
Dexamethasone
Online Access:https://doi.org/10.1186/s12978-025-01965-8
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https://doi.org/10.1186/s12978-025-01965-8

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