Evaluation of serum ESPL1 as a biomarker for early diagnosis of HBV-related hepatocellular carcinoma

Evaluation of serum ESPL1 as a biomarker for early diagnosis of HBV-related hepatocellular carcinoma

ObjectiveTo evaluate the reliability of serum human phosphorylated exospindle polar-like proteinase 1 (ESPL1) as a serum biomarker for early diagnosis of hepatitis B virus (HBV)-related hepatocellular carcinoma (HBV-HCC).MethodsThis retrospective study was conducted on 266 patients with chronic hepa...

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Main Authors: Lu-Huai Feng, Lu Wei, Bobin Hu, Hengkai Liang, Qingmei Li, Qianbing Yin, Tumei Su, Long Huang, Hongqian Liang, Jianning Jiang, Minghua Su
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Oncology
Subjects:
hepatocellular carcinoma
alpha-fetoprotein
early diagnosis
HBV S gene fusion
biomarker
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1574317/full
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https://www.frontiersin.org/articles/10.3389/fonc.2025.1574317/full

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