Metallaphotoredox-catalyzed alkynylcarboxylation of alkenes with CO2 and alkynes for expedient access to β-alkynyl acids

Abstract Carboxylation with CO2 offers an attractive and sustainable access to valuable carboxylic acids. Among these methods, direct C−H carboxylation of terminal alkynes with CO2 has attracted much attention for one-carbon homologation of alkynes, enabling rapid synthesis of propiolic acids. In co...

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Bibliographic Details
Main Authors: Jin-Cheng Xu, Jun-Ping Yue, Min Pan, Yi-Chi Chen, Wei Wang, Xi Zhou, Wei Zhang, Jian-Heng Ye, Da-Gang Yu
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-57060-w
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