Cancer cell-derived exosomal miR-34a inhibits the malignant progression of pancreatic adenocarcinoma cells by restraining the M2 polarization of macrophages

This study aimed to investigate the crosstalk mechanism between pancreatic cancer (PAC) cells and M2 tumor-associated macrophages induced by tumor-derived exosomal miR-34a. MicroRNA and mRNA expression levels were detected using RT-qPCR. Cell Counting Kit-8, wound-healing, transwell assays and flow...

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Bibliographic Details
Main Authors: Kui Long, Xiang Kui, Qingbin Zeng, Wenzhi Dong
Format: Article
Language:English
Published: PAGEPress Publications 2025-04-01
Series:European Journal of Histochemistry
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Online Access:https://www.ejh.it/index.php/ejh/article/view/4176
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