Innovative spiral nerve conduits: Addressing nutrient transport and cellular activity for critical-sized nerve defects

Innovative spiral nerve conduits: Addressing nutrient transport and cellular activity for critical-sized nerve defects

Large-gap nerve defects require nerve guide conduits (NGCs) for complete regeneration and muscle innervation. Many NGCs have been developed using various scaffold designs and tissue engineering strategies to promote axon regeneration. Still, most are tubular with inadequate pore sizes and lack surfa...

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Bibliographic Details
Main Authors: Allen Zennifer, S.K. Praveenn Kumar, Shambhavi Bagewadi, Swathi Unnamalai, Davidraj Chellappan, Sama Abdulmalik, Xiaojun Yu, Swaminathan Sethuraman, Dhakshinamoorthy Sundaramurthi, Sangamesh G. Kumbar
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-02-01
Series:Bioactive Materials
Subjects:
Nerve guide conduits
Spiral micro-nanostructures
Large-gap nerve defect
Poly(3-hydroxybutyrate-co-3-hydroxy valerate) (PHBV)
Thermoplastic polyurethane (TPU)
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X2400481X
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