Association of Kidney Graft Long-term Outcome With Recipient Cystathionine Gamma-lyase Polymorphisms and Hydrogen Sulfide Levels: A Cohort Study

Association of Kidney Graft Long-term Outcome With Recipient Cystathionine Gamma-lyase Polymorphisms and Hydrogen Sulfide Levels: A Cohort Study

Background. Hydrogen sulfide (H2S) produced endogenously by the CTH gene-encoded cystathionine gamma-lyase protects from renal ischemia–reperfusion injury in preclinical models. Here, we hypothesized that CTH gene polymorphisms (single nucleotide polymorphism [SNP]) and recipient H2S serum levels in...

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Main Authors: Matthieu Halfon, MD, Raffaella Emsley, Thomas Agius, PhD, Arnaud Lyon, Sébastien Déglise, MD, Manuel Pascual, MD, Korkut Uygun, PhD, Heidi Yeh, MD, Leonardo V. Riella, MD, PhD, James F. Markmann, MD, PhD, Pierre-Yves Bochud, MD, Dela Golshayan, MD, PhD, Alban Longchamp, MD, PhD, the Swiss Transplant Cohort Study
Format: Article
Language:English
Published: Wolters Kluwer 2025-05-01
Series:Transplantation Direct
Online Access:http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000001779
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http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000001779

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