Transcriptomic and Functional Landscape of Adult Human Spinal Cord NSPCs Compared to iPSC-Derived Neural Progenitor Cells

Transcriptomic and Functional Landscape of Adult Human Spinal Cord NSPCs Compared to iPSC-Derived Neural Progenitor Cells

The adult human spinal cord harbors diverse populations of neural stem/progenitor cells (NSPCs) essential for neuroregeneration and central nervous system repair. While induced pluripotent stem cell (iPSC)-derived NSPCs offer significant therapeutic potential, understanding their molecular and funct...

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Bibliographic Details
Main Authors: Sasi Kumar Jagadeesan, Ahmad Galuta, Ryan Vimukthi Sandarage, Eve Chung Tsai
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Cells
Subjects:
spinal cord injury
neural stem/progenitor cells
induced pluripotent stem cells
transcriptomics
neurogenesis
differentiation potential
Online Access:https://www.mdpi.com/2073-4409/14/2/64
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