LncRNA PVT1 promotes cuproptosis through transcriptional activation of FDX1 in colorectal cancer

Background: Cuproptosis, a copper-dependent form of regulated cell death, has emerged as a redox-sensitive vulnerability in cancer. However, the molecular basis by which this process is initiated and sustained in tumors remains poorly defined. Methods: We investigated the functional role of FDX1 in...

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Bibliographic Details
Main Authors: Jinyan Ma, Yingjie Zhang, Zhuoran Sun, Hui Guo, Xiang Li, Jueting Cai, Meichen Zhang, Mengmeng Chen, Jingjing Jiang, Lingling Zhang
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Redox Biology
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Online Access:http://www.sciencedirect.com/science/article/pii/S2213231725002356
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