Patient-Oriented In Vitro Studies in Duchenne Muscular Dystrophy: Validation of a 3D Skeletal Muscle Organoid Platform

Patient-Oriented In Vitro Studies in Duchenne Muscular Dystrophy: Validation of a 3D Skeletal Muscle Organoid Platform

<b>Background:</b> Three-dimensional skeletal muscle organoids (3D SkMO) are becoming of increasing interest for preclinical studies in Duchenne muscular dystrophy (DMD), provided that the used platform demonstrates the possibility to form functional and reproducible 3D SkMOs, to investi...

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Main Authors: Raffaella Quarta, Enrica Cristiano, Mitchell K. L. Han, Brigida Boccanegra, Manuel Marinelli, Nikolas Gaio, Jessica Ohana, Vincent Mouly, Ornella Cappellari, Annamaria De Luca
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Biomedicines
Subjects:
Duchenne muscular dystrophy
3D skeletal muscle organoid
tissue engineering
immortalized human myoblast
disease modeling
Online Access:https://www.mdpi.com/2227-9059/13/5/1109
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