Population screening of adults identifies novel genetic variants associated with celiac disease

Population screening of adults identifies novel genetic variants associated with celiac disease

Abstract Celiac disease (CeD) is an autoimmune disease driven by a complex genetic interplay within and beyond the human leukocyte antigen (HLA) region. Despite this, half of its heritability remains unexplained, with most of the unidentified variants located in non-protein coding regions. Here we p...

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Main Authors: Mohammad Sayeef Alam, Laurent Thomas, Ben Brumpton, Kristian Hveem, Knut E. A. Lundin, Sebo Withoff, Iris H. Jonkers, Ludvig M. Sollid, Rebecka Hjort, Eivind Ness-Jensen
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Scientific Reports
Subjects:
Celiac
Gluten
Autoimmune
GWAS
Non-HLA
Online Access:https://doi.org/10.1038/s41598-025-04421-6
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https://doi.org/10.1038/s41598-025-04421-6

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