Mild autonomous cortisol secretion leads to reduced volumetric BMD at lumbar spine in patients with primary aldosteronism

Mild autonomous cortisol secretion leads to reduced volumetric BMD at lumbar spine in patients with primary aldosteronism

ObjectivesGlucocorticoid cosecretion is more common in primary aldosteronism (PA) than previously thought. Chronic subtle cortisol excess in patients with mild autonomous cortisol secretion (MACS) negatively affects bone health. This study aimed to evaluate the impact of MACS on bone density and tur...

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Main Authors: Nabeel Mansour, Denise Bruedgam, Daniel Heinrich, Ulrich Dischinger, Nicole Reisch, Friederike Völter, Isabel Stüfchen, Elisabeth Nowak, Stephanie Zopp, Victoriya Vasileva, Osman Öcal, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Martin Bidlingmaier, Martin Reincke, Juínia Ribeiro de Oliveira Longo Schweizer
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Endocrinology
Subjects:
MACs
Conn’s syndrome
primary aldosteronism
volumetric bone mineral density
bone turnover markers
cortisol
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2024.1521680/full
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https://www.frontiersin.org/articles/10.3389/fendo.2024.1521680/full

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