Case-Only Survival Analysis Reveals Unique Effects of Genotype, Sex, and Coronary Disease Severity on Survivorship.

Case-Only Survival Analysis Reveals Unique Effects of Genotype, Sex, and Coronary Disease Severity on Survivorship.

Survival bias may unduly impact genetic association with complex diseases; gene-specific survival effects may further complicate such investigations. Coronary artery disease (CAD) is a complex phenotype for which little is understood about gene-specific survival effects; yet, such information can of...

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Main Authors: Jennifer R Dungan, Xuejun Qin, Benjamin D Horne, John F Carlquist, Abanish Singh, Melissa Hurdle, Elizabeth Grass, Carol Haynes, Simon G Gregory, Svati H Shah, Elizabeth R Hauser, William E Kraus
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0154856&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0154856&type=printable

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