Enhanced cell stress response and protein degradation capacity underlie artemisinin resistance in Plasmodium falciparum
ABSTRACT Malaria remains a global health burden, killing over half a million people each year. Decreased therapeutic efficacy to artemisinin, the most efficacious antimalarial, has been detected in sub-Saharan Africa, a worrying fact given that over 90% of deaths occur on this continent. Mutations i...
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| Main Authors: | Melissa R. Rosenthal, Sukhithasri Vijayrajratnam, Tessa M. Firestone, Caroline L. Ng |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
American Society for Microbiology
2024-11-01
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| Series: | mSphere |
| Subjects: | |
| Online Access: | https://journals.asm.org/doi/10.1128/msphere.00371-24 |
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