Enhanced cell stress response and protein degradation capacity underlie artemisinin resistance in Plasmodium falciparum

ABSTRACT Malaria remains a global health burden, killing over half a million people each year. Decreased therapeutic efficacy to artemisinin, the most efficacious antimalarial, has been detected in sub-Saharan Africa, a worrying fact given that over 90% of deaths occur on this continent. Mutations i...

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Bibliographic Details
Main Authors: Melissa R. Rosenthal, Sukhithasri Vijayrajratnam, Tessa M. Firestone, Caroline L. Ng
Format: Article
Language:English
Published: American Society for Microbiology 2024-11-01
Series:mSphere
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Online Access:https://journals.asm.org/doi/10.1128/msphere.00371-24
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