Comparison of diagnostic accuracy of microscopy and flow cytometry in evaluating N-methyl-D-aspartate receptor antibodies in serum using a live cell-based assay.

Comparison of diagnostic accuracy of microscopy and flow cytometry in evaluating N-methyl-D-aspartate receptor antibodies in serum using a live cell-based assay.

N-methyl-D-aspartate receptor (NMDAR) encephalitis is an autoimmune neurological disease, diagnosed by a specific autoantibody against NMDAR. Antibody testing using commercially available cell-based assays (CBA) or immunohistochemistry on rat brain tissue has proven high specificity and sensitivity....

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Main Authors: Melanie Ramberger, Patrick Peschl, Kathrin Schanda, Regina Irschick, Romana Höftberger, Florian Deisenhammer, Kevin Rostásy, Thomas Berger, Josep Dalmau, Markus Reindl
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0122037&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0122037&type=printable

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